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T7589 |
Afamelanotide acetate
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afamelanotide |
Melanocortin Receptor
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Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria. |
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TP1097 |
Melanotan I
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[Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I |
Others
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Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an α-melanocyte-stimulating hormone (α-MSH) analog, which is injected subcutaneously to increase the amount of melanin in the skin Melanotan I is used as... |
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T67703 |
MTOR inhibitor 9b
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mTOR
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mTOR inhibitor 9b is an enzyme inhibitor of protein kinase mTOR he phosphatidylinositol 3-kinase PIK3CA with IC50s of 0.76 nm and 1.262 µM, respectively.mTOR inhibitor 9b possesses anticancer activity and can be used to ... |
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T11847L |
Liarozole
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R75251 dihydrochloride |
P450
,
Retinoid Receptor
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Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 1... |
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T1120L2 |
Dacarbazine citrate
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DTIC citrate |
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Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Sof... |
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T11847 |
Liarozole dihydrochloride
|
R75251 dihydrochloride |
Others
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Liarozole dihydrochloride is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lya... |
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T72188 |
Nicotinamide Hydrochloride
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Niacinamide Hydrochloride,Nicotinic acid amide Hydrochloride,Niacinamide Hydrochloride ; Nicotinic acid amide Hydrochloride |
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Nicotinamide Hydrochloride is a form of vitamin B3 or niacin that inhibits sirtuin 2 ( SIRT2 ) activity in vitro , with an EC 50 of 2 μM. Nicotinamide Hydrochloride inhibits up to 90% melanoma cell number and increases c... |
